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The Rise of Patient-Centered Outcomes Research
24 January 2012
Rachael Fleurence
The newly formed US Patient-Centered Outcomes Research Institute (PCORI) has been tasked with “helping people make informed health care decisions and improving health care delivery and outcomes by pro...
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The Ends Justify the Mean: Outcome Measures for Estimating the Value of New Cancer Therapies
16 January 2012
Andrew Davies, Andrew Briggs, John Schneider, Adrian Levy, Omar Ebeid, Samuel Wagner, Srividya Kotapati, Scott Ramsey
Abstract: Objective: Overall survival is a commonly reported end point in clinical trial publications, and a key determinant of therapies’ cost-effectiveness. Patients’ survival times have skewed dist...
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The Quality-of-Life Impact of Head and Neck Cancer: Preference Values from the Canadian General Public
19 December 2011
Shelagh M. Szabo, Rosie L. Dobson, Bonnie M.K. Donato, Gil L’Italien, Sebastien J. Hotte, Adrian R. Levy
Abstract: Objectives: To elicit preferences for standardized head and neck cancer (HNC) health states describing the health-related quality of life (HRQoL) impact of cancer type or stage, progression,...
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Health Outcomes of Interest in Observational Data: Issues in Identifying Definitions in the Literature
28 November 2011
Paul E. Stang, Patrick B. Ryan, Stacie B. Dusetzina, Abraham G. Hartzema, Christian Reich, J. Marc Overhage, Judith A. Racoosin
Abstract: Objectives: To describe the literature search strategies and results to inform development of health outcomes of interest (HOI) definitions studied within the Observational Medical Outcomes ...
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Health Care Utilization and Costs in Patients with Generalized Anxiety Disorder Initiating Add-on Therapy with Benzodiazepines
14 November 2011
Ariel Berger, John Edelsberg, Vamsi Bollu, Jose Ma. J. Alvir, Ashish Dugar, Ashish V. Joshi, Gerry Oster
Abstract: Objectives: To examine patterns of health care utilization and costs in patients with generalized anxiety disorder (GAD) who begin treatment with benzodiazepine anxiolytics as add-on therapy...
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